Cathrine Anne O'Hara is a Canadian-American actress, writer and comedian. She is known for her comedy work on Second City Television (1976-84) and in films such as After Hours (1985), Beetlejuice (1988), Home Alone (1990), Home Alone 2: Lost in New York (1992), and The Nightmare Before (1993). Her other film appearances include the mockumentary films written and directed by Christopher Guest; Waiting for Guffman (1996), Best in Show (2000), A Mighty Wind (2003), and For Your Consideration (2006).
O'Hara won the 1982 Primetime Emmy Award for Outstanding Writing for a Variety Series for SCTV Network, the Genie Award for Best Supporting Actress for the 1999 film The Life Before This, and was nominated for an Emmy Award for the 2010 television film Temple Grandin. Since 2015, she has starred as Moira Rose on the CBC sitcom Schitt's Creek, for which she won the 2016 Canadian Screen Award for Best Lead Actress in a Comedy Series.